Journal américain de l'administration avancée de médicaments Libre accès

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Multiple Unit Drug Delivery System:Pelletization Techniques

S.Ramu, G.Ramakrishna, M.Balaji, K.Kondala rao, S.Haranadh reddy, D.pavan kumar

The present study aims at discussing the potential advantages of multiple unit dosage forms (pellets etc.) over the single unit dosage forms (tablets). Pelletization is a novel drug delivery system; a technique which converts fine powder particles into pellets. Review deals with the pellet and its various types of pelletization techniques like spheronization and extrusion, pelletization by layering, pelletiztion by solution layering &direct pelletization.The advantages, disadvantages & various applications of above mentioned techniques.spheronization and extrusion pelletization by layering are most widely used techniques.The study also deals with factors and evaluation of pellets.