Sabiha Imran
As The respiratory disorders caused by novel corona virus covid-19 (SARS-CoV-2) are a highly contagious disease. The World Health Organization (WHO) has declared the ongoing outbreak has declared as pandemic by World Health Organization (WHO) and it is a global public health emergency. Corona viruses (CoV) belong to the family Coronaviridae with its high mutation rate .The covid19 virus is differ from other corona viruses is inducing the potent a storm of pro inflammatory cytokines that causes the exhaustion of T cells , a state of poor effectors function. The innate and adaptive immune system responds vigorously to get rid of Covid-19 infection. The innate immune response, which is first line of defense against virus, consists of important tools like complement system, interferons and the adaptive immune response soldiers like monocytes, neutrophils lymphocytes fight against virus and cooperate to each other also. The infection becomes severe where immune system is compromised especially the elderly individuals if having diabetes, tuberculosis or cancer are more prone to severe infection. Currently, enormous efforts in the research on novel corona virus are in progress. This study is in the ancipitation to understand better the interaction of human immune system to COVID-19 so that it could help to design effective immunotherapy against the Corona virus.
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