European Journal of Experimental Biology Libre accès

Abstrait

Antimycotic activity of some medicinal plants on aquatic fungi

This study shows the medicinal plant sources commonly used against various aetiological agents and recently being incorporated into some pharmaceutical products. Various plant sources used for the purpose of this study include Azadirachta indica, Ocimum gratissimum, Jatropha species and Carica papaya. Fungal species isolated from aquatic sources during the study include Candida species, Rhizopus spp, Rhizomucor spp, Mucor spp, Aspergillus spp and Penicillium spp. Fungal species such as Candida spp, Rhizopus spp and Mucor spp were found to be common to the three forms of water sources used, that is, the fast moving water, the slow moving water and well which is relatively stagnant. The presence of fungal species in the sampled water sources may be indicative of plant debris contamination from other environmental sources such as soil. The evaluation of the antimycotic properties of these plant extract determined through the antifungal activity from these sources showed their potency against most of the fungal isolates with different levels of growth inhibition. Out of the four plant sources tested, extract from Azadirachta indica was found to be most active with inhibition zone greater than 15mm and total growth inhibition in some instances against the fungal isolates while Carica papaya extracts has lowest activity. This signifies that the active medicinal plant source can be optimized for future antimycotic therapy in diseases control and may solve some antimicrobial resistance problems being products from natural origin.

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