Atmane Seba
Acute kidney Injury (AKI) is characterized by a reversible increase in the blood concentration of creatinine and nitrogenous waste products and by the inability of the kidney to regulate fluid and electrolyte homeostasis appropriately. There are many causes of AKI. Some causes of AKI, such as rapidly progressive glomerulonephritis (RPGN), maypresent as AKI but rapidly evolve into chronic kidney disease (CKD).Several renal diseases, such as the hemolytic–uremic syndrome (HUS), Henoch– Schönlein purpura, and obstructive uropathy with associated renaldysplasia, maypresent as AKI withimprovement of renal function to normal or near-normal levels, but the child’srenal function may slowly deteriorate, leading to CKD several months to yearslater.Ourstudyisretrospective. It was conducted in the Department of Nephrology of the UniversityHospital Center (UHC) of TiziOuzou, between 2015 and 2018. They were selectedfrom the hospitalizationregister of ourdepartment. Weincluded all childrenwith acute renal injury duringthis time period. Data was collected from patients’ medical records. Over the four years, 26 patients (34% male and 64% femals) with a medianage of 7 years (range 40 days to 15 years) weremanaged. The most affected age group in our study is [12-16] with a frequency of 36%..The circumstances of discovery in the majority of our patients beingrevealed by digestive signs (diarrhea, vomiting) and related to the etiology of AKI (HUS post diarrhea). In ourstudy, 44% of the patients have thrombocytopenia associated with AKI; and thisis due to the origin of this syndrome (Atypical HUS). The etiology of AKI: Nephropathy glomerularin 37% hemolytic and uremic syndromin 54% and obstructive nephropathyin 9%. Patients survived in 92 % of the cases and 58% of them had a normal renal function. We had 7% of death. Peritoneal dialysis is the most commonly used emergency treatment for AKI in childrenat a frequency of 37%.
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