Vahideh Sahraiian, Sima Nasri, Mohammad Mousaei, Shabnam Kolahi and Fatemeh Mahdi
Adiponectin is a adipocytokines that it secretes of Adipose tissue and regulate glucose, lipid metabolism and vascular function. This protein is related Inversely with cardiovascular risk factors like blood pressure. Cardiovascular disease, have irreparable effects on individuals, including pregnant women. Blood pressure, is a major cause of maternal death in brain and heart’s different incidents. In developed countries, 16% of maternal deaths is related to blood pressure abnormalities. Of course 50% of these women can survive with intensive care. The most common cardiovascular disease during pregnancy, is hypertension that can endanger mother and Embryo life , so this research focus will be on this topic. This clinical test did on 110 pregnant women including two groups. 63 patients did with high blood pressure and 47 women did controls group with normal blood pressure . Groups were in terms of the same age range (18-35 years) and time of sampling (late third quarter, near the end of pregnancy and between 10-13 Am).Their blood pressure were measured with Barometer apparatus and their serum adiponectin levels were measured with by adiponectin ELISA kit. Also measured their BMI. Investigation showed that adiponectin levels are associated inversely with blood pressure during pregnancy. Presumably Deficiency of Adiponectin in pregnant women with high blood pressure, prevent to increase blood volume. So during the adaptive process, increase vascular spasms and vascular resistance that is responsible for high blood pressure and arterial vascular injury.
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